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Anti Phospholipid Antibodies and Cell Apoptosis
  • What are Phospholipids
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What are Phospholipids
  • Phospholipids are lipids. Each molecule is made up of one glycerol molecule attached to two fatty acids and a phosphate group. Structurally, phospholipids are similar to triglycerides except that a phosphate group replaces one of the fatty acids. Phospholipid molecules have one end which is attracted to water while the other is repelled by it. This property is important in plasma membranes. The fatty acid end is not attracted to water and is called hydrophobic. At the other end of the molecule the phosphate group is attracted to water, it is said to be hydrophilic.
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What are Phospholipids
  • Membrane phospholipids are relatively small molecules that possess both hydrophobic and hydrophilic components. These phospholipids spontaneously form closed bimolecular sheets in aqueous solution, and provide a barrier to the movement of polar molecules.


  • Membrane proteins have many functions including gates, pumps, receptors, energy transducers, cell recognition proteins, and catalytic enzymes. Proteins can be located on the outside surface, inside surface, or span the the membrane, depending on the function of the protein.
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What are Phospholipids
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Anti Phospholipid Antibodies and Cell Apoptosis
  • What are Anti-Phospholipid Antibodies
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What are Anti-Phospholipid Antibodies
  • AP Antibodies are Auto (directed at ones self) antibodies produced by our own immune system.


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What are Anti-Phospholipid Antibodies
  • AP Antibodies react with the positive / negative charge of the Phospholipids and reverse their polarity.


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What are Anti-Phospholipid Antibodies
  • This reversal then compromises the protective bilayer
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Anti Phospholipid Antibodies and Cell Apoptosis
  • Cell Death
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Cell Death
  • Our cells are controlled by the natural DNA programming that has evolved over the centuries to protect us from attacks on our cells.
  • As the cells under attack become ‘compromised’ a natural system of self destruction occurs.
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Cell Death
  • This programmed self destruction is called Apoptosis.


  • From these simple natural actions and reactions within our immune system we can deduce the AP Antibody is directly responsible for cell death.