Results from data received up to 1st February 2005
Questions	Total completed surveys	%	Total prior to diagnosis	%	Number of patients with symptoms since diagnosis	% of patients with new symptoms (after diagnosis)	% of patients with this symptom which appeared after diagnosis
	351	100.00%
Gender
Female	311	88.60%
Male	40	11.40%
Ages in 10 year groups
Up to 30	63	17.95%
31 to 40	131	37.32%
41 to 50	114	32.48%
51 to 60	45	12.82%
61 and over	19	5.41%
Country
UK	60	17.09%
USA	240	68.38%
Poland	1	0.28%
Brazil	1	0.28%
Australia	16	4.56%
Canada	18	5.13%
India	1	0.28%
South Africa	2	0.57%
Spain	1	0.28%
Egypt	1	0.28%
New Zealand	2	0.57%
Italy	1	0.28%
Norway	1	0.28%
Jamaica	1	0.28%
Eire	1	0.28%
Philippines	1	0.28%
France	1	0.28%
Israel	1	0.28%
Information withheld on Country	1	0.28%
Number of Doctors before diagnosis (mean average)	6
Have you been diagnosed with MS	17	4.84%	15	4.27%	2	0.57%	11.76%
Have you been diagnosed with Lupus	69	19.66%	24	6.84%	45	12.82%	65.22%
Occular
Blurred or double vision	178	50.71%	0	0.00%	178	50.71%	100.00%
Visual disturbance	211	60.11%	128	36.47%	83	23.65%	39.34%
Visual loss	110	31.34%	73	20.80%	37	10.54%	33.64%
Retinal artery occlusion	17	4.84%	7	1.99%	10	2.85%	58.82%
Retinal vein thrombosis	11	3.13%	5	1.42%	6	1.71%	54.55%
Cardiorespiratory
Chest pain	178	50.71%	115	32.76%	63	17.95%	35.39%
Radiating arm pain	118	33.62%	74	21.08%	44	12.54%	37.29%
Shortness of breath	170	48.43%	117	33.33%	53	15.10%	31.18%
Cardiac
Insufficiency murmur	66	18.80%	35	9.97%	31	8.83%	46.97%
Myocardial infarction	47	13.39%	18	5.13%	29	8.26%	61.70%
Gastrointestinal
Abdominal pain	162	46.15%	107	30.48%	55	15.67%	33.95%
Abdominal distension	164	46.72%	105	29.91%	59	16.81%	35.98%
Abdominal migraine	49	13.96%	35	9.97%	14	3.99%	28.57%
Emesis (vomiting)	54	15.38%	36	10.26%	18	5.13%	33.33%
Right upper quadrant	44	12.54%	31	8.83%	13	3.70%	29.55%
Abdominal tenderness	47	13.39%	29	8.26%	18	5.13%	38.30%
Pulmonary
Respiratory distress	78	22.22%	53	15.10%	25	7.12%	32.05%
Tachypnea	53	15.10%	38	10.83%	15	4.27%	28.30%
Pulmonary embolism	67	19.09%	48	13.68%	19	5.41%	28.36%
Pulmonary hypertension	29	8.26%	14	3.99%	15	4.27%	51.72%
Peripheral Vascular
Leg pain	213	60.68%	140	39.89%	73	20.80%	34.27%
Leg swelling	152	43.30%	103	29.34%	49	13.96%	32.24%
Claudication	148	42.17%	89	25.36%	59	16.81%	39.86%
Digital ulcerations	37	10.54%	19	5.41%	18	5.13%	48.65%
Leg ulcerations	20	5.70%	12	3.42%	8	2.28%	40.00%
Cold-induced finger and/or toe pain	159	45.30%	106	30.20%	53	15.10%	33.33%
Bone infarction	114	32.48%	75	21.37%	39	11.11%	34.21%
Avascular necrosis	109	31.05%	64	18.23%	45	12.82%	41.28%
Limb swelling (DVT)	106	30.20%	77	21.94%	29	8.26%	27.36%
Peripheral edema	56	15.95%	31	8.83%	25	7.12%	44.64%
Decreased capillary refill	30	8.55%	16	4.56%	14	3.99%	46.67%
Decreased pulses	34	9.69%	18	5.13%	16	4.56%	47.06%
Decreased perfusion	21	5.98%	12	3.42%	9	2.56%	42.86%
Gangrene	7	1.99%	5	1.42%	2	0.57%	28.57%
Musculoskeletal
Bone pain	155	44.16%	97	27.64%	58	16.52%	37.42%
Joint pain	236	67.24%	153	43.59%	83	23.65%	35.17%
Cutaneous
Purpuric and/or petechial rashes	37	10.54%	16	4.56%	21	5.98%	56.76%
Livedo reticularis	29	8.26%	15	4.27%	14	3.99%	48.28%
Dusky fingers and/or toes	49	13.96%	31	8.83%	18	5.13%	36.73%
Blanching of fingers and/or toes	57	16.24%	39	11.11%	18	5.13%	31.58%
Purpuric lesions	23	6.55%	11	3.13%	12	3.42%	52.17%
Superficial thrombophlebitis	40	11.40%	23	6.55%	17	4.84%	42.50%
Vasospasm	79	22.51%	56	15.95%	23	6.55%	29.11%
Splinter hemorrhages	14	3.99%	9	2.56%	5	1.42%	35.71%
Peripheral infarctions	11	3.13%	7	1.99%	4	1.14%	36.36%
Skin ulcerations	11	3.13%	7	1.99%	4	1.14%	36.36%
Bruising	34	9.69%	16	4.56%	18	5.13%	52.94%
Neurological and Psychiatric
Syncope	54	15.38%	37	10.54%	17	4.84%	31.48%
Seizures	66	18.80%	41	11.68%	25	7.12%	37.88%
Headache (migraine)	253	72.08%	184	52.42%	69	19.66%	27.27%
Ascending weakness	137	39.03%	83	23.65%	54	15.38%	39.42%
Tremors	118	33.62%	72	20.51%	46	13.11%	38.98%
Memory loss	228	64.96%	121	34.47%	107	30.48%	46.93%
Problems with concentrating, reading comprehension, calculations (change in performance)	233	66.38%	129	36.75%	104	29.63%	44.64%
Stroke/CVA (cerebrovascular accident)	86	24.50%	55	15.67%	31	8.83%	36.05%
TIA	128	36.47%	74	21.08%	54	15.38%	42.19%
vasovasorum(or blood vessel) ischemia/infarction	77	21.94%	48	13.68%	29	8.26%	37.66%
Paralysis,	62	17.66%	35	9.97%	27	7.69%	43.55%
Abnormal movements	71	20.23%	38	10.83%	33	9.40%	46.48%
Multiple sclerosis-like disorder	140	39.89%	75	21.37%	65	18.52%	46.43%
Endocrine
Weakness	212	60.40%	123	35.04%	89	25.36%	41.98%
Fatigue	268	76.35%	161	45.87%	107	30.48%	39.93%
Arthralgia	107	30.48%	71	20.23%	36	10.26%	33.64%
Abdominal pain	77	21.94%	47	13.39%	30	8.55%	38.96%
Adrenal infarction/hemorrhage	34	9.69%	19	5.41%	15	4.27%	44.12%
Genitourinary
Hematuria (blood in urine)	55	15.67%	29	8.26%	26	7.41%	47.27%
Peripheral edema	64	18.23%	42	11.97%	22	6.27%	34.38%
Renal
Hypertension	69	19.66%	29	8.26%	40	11.40%	57.97%
Renal artery thrombosis	8	2.28%	3	0.85%	5	1.42%	62.50%
Intrarenal vascular lesions (scar tissue)	16	4.56%	6	1.71%	10	2.85%	62.50%
Hematuria (blood in urine)	53	15.10%	26	7.41%	27	7.69%	50.94%
Renal vein thrombosis	7	1.99%	2	0.57%	5	1.42%	71.43%
Pregnancy Related
Miscarriages (Number of Patients)	173	49.29%	173	49.29%	0	0.00%	0.00%
Premature birth (Number of Patients)	76	21.65%	57	16.24%	19	5.41%	25.00%
IUGR	30	8.55%	15	4.27%	15	4.27%	50.00%
Oligohydramnios	25	7.12%	17	4.84%	8	2.28%	32.00%
Chorea gravidarum	14	3.99%	8	2.28%	6	1.71%	42.86%
Placental infarction	37	10.54%	23	6.55%	14	3.99%	37.84%
Preeclampsia	54	15.38%	36	10.26%	18	5.13%	33.33%
Toxemia of pregnancy	40	11.40%	24	6.84%	16	4.56%	40.00%
Neonatal thromboembolism	11	3.13%	7	1.99%	4	1.14%	36.36%
Diagnosed APS during tests at pregnancy	153	43.59%	0	0.00%	0	0.00%	99.72%
Family History
Pregnancy related family history	86	24.50%	Relationship to pre or post diagnosis is immaterial
Family history of MI or stroke	56	15.95%
Family history of DVT, Phlebitis or PE	90	25.64%
Family History of Migraine, Reynaud's or TIA's	123	35.04%
Medical History
Use of Oral Contraception during tests at pregnancy	98	27.92%	Relationship to pre or post diagnosis is immaterial
Other long-term use of medication	176	50.14%
Vaccinations
vaccinations	274	78.06%	Relationship to pre or post diagnosis is immaterial
Trauma or Stress Related
Traumatic or stressful event prior to onset	258	73.50%	Relationship to pre or post diagnosis is immaterial
Other Symptoms
Back pain	16	4.56%
Pain in side of ribs (flank)	5	1.42%
Heat sensitivity	4	1.14%
Sun sensitivity	6	1.71%
Nasal ulcers	6	1.71%
Blood blisters in mouth	2	0.57%
Mouth ulcers	7	1.99%
Psoriatic Arthritis	2	0.57%
Muscle cramps	3	0.85%
Sinus problems	5	1.42%